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Liao, James

One or more keywords matched the following items that are connected to Liao, James

Item Type	Name
Concept	rho-Associated Kinases
Academic Article	Rho-kinase mediates hypoxia-induced downregulation of endothelial nitric oxide synthase.
Academic Article	Inhibition of Rho-kinase leads to rapid activation of phosphatidylinositol 3-kinase/protein kinase Akt and cardiovascular protection.
Academic Article	Rho-kinase mediates hyperglycemia-induced plasminogen activator inhibitor-1 expression in vascular endothelial cells.
Academic Article	Increased Rho kinase activity in a Taiwanese population with metabolic syndrome.
Academic Article	Identification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damage.
Academic Article	A method for measuring Rho kinase activity in tissues and cells.
Academic Article	Inhibition of Rho kinase (ROCK) leads to increased cerebral blood flow and stroke protection.
Academic Article	Decreased perivascular fibrosis but not cardiac hypertrophy in ROCK1+/- haploinsufficient mice.
Academic Article	Increased leukocyte rho kinase (ROCK) activity and endothelial dysfunction in cigarette smokers.
Academic Article	Calcium channel blocker and Rho-associated kinase activity in patients with hypertension.
Academic Article	ROCK inhibition prevents fetal serum-induced alteration in structure and function of organ-cultured mesenteric artery.
Academic Article	Increased leukocyte Rho-associated coiled-coil containing protein kinase activity predicts the presence and severity of coronary vasospastic angina.
Academic Article	Increased Rho kinase activity in congestive heart failure.
Academic Article	Statins inhibit Rho kinase activity in patients with atherosclerosis.
Academic Article	Statins and cardiovascular diseases: from cholesterol lowering to pleiotropy.
Academic Article	Rho-associated coiled-coil-forming kinases (ROCKs): potential targets for the treatment of atherosclerosis and vascular disease.
Academic Article	Role of Rho kinase isoforms in murine allergic airway responses.
Academic Article	Measurement of Rho-associated kinase (ROCK) activity in humans: validity of leukocyte p-MBS/t-MBS in comparison with vascular response to fasudil.
Academic Article	Rho-associated coiled-coil-containing kinase 2 deficiency in bone marrow-derived cells leads to increased cholesterol efflux and decreased atherosclerosis.
Academic Article	Deficiency of ROCK1 in bone marrow-derived cells protects against atherosclerosis in LDLR-/- mice.
Academic Article	Roles of rho-associated kinase and oxidative stress in the pathogenesis of aortic stiffness.
Academic Article	Evidence for statin pleiotropy in humans: differential effects of statins and ezetimibe on rho-associated coiled-coil containing protein kinase activity, endothelial function, and inflammation.
Academic Article	Rho kinase: an important mediator of atherosclerosis and vascular disease.
Academic Article	Rho-associated kinase activity, endothelial function, and cardiovascular risk factors.
Academic Article	Rho kinase inhibition improves endothelial function in human subjects with coronary artery disease.
Academic Article	Activated Rho kinase mediates diabetes-induced elevation of vascular arginase activation and contributes to impaired corpora cavernosa relaxation: possible involvement of p38 MAPK activation.
Academic Article	Rho-kinase inhibition: a novel therapeutic target for the treatment of cardiovascular diseases.
Academic Article	Does it matter whether or not a lipid-lowering agent inhibits Rho kinase?
Academic Article	Mineralocorticoid receptor blocker eplerenone improves endothelial function and inhibits Rho-associated kinase activity in patients with hypertension.
Academic Article	ROCK1 & 2 perform overlapping and unique roles in angiogenesis and angiosarcoma tumor progression.
Academic Article	Elevated rho-kinase activity as a marker indicating atherosclerosis and inflammation burden in polyvascular disease patients with concomitant coronary and peripheral arterial disease.
Academic Article	Rho-kinase: a potential link between hypercholesterolemia and abnormal vascular smooth muscle contraction.
Academic Article	Comparison of effects of rosuvastatin (10 mg) versus atorvastatin (40 mg) on rho kinase activity in caucasian men with a previous atherosclerotic event.
Academic Article	The Rho kinases: critical mediators of multiple profibrotic processes and rational targets for new therapies for pulmonary fibrosis.
Academic Article	Phosphorylation of IRF4 by ROCK2 regulates IL-17 and IL-21 production and the development of autoimmunity in mice.
Academic Article	Abrogation of airway hyperresponsiveness but not inflammation by rho kinase insufficiency.
Academic Article	Evidence of pleiotropy by statins: leukocyte Rho kinase (ROCK) activity and pretreated statin before percutaneous coronary interventions are clinical vascular outcome predictors.
Academic Article	Rho-kinase inhibition acutely augments blood flow in focal cerebral ischemia via endothelial mechanisms.
Academic Article	Critical role of exogenous nitric oxide in ROCK activity in vascular smooth muscle cells.
Academic Article	ROCKs as therapeutic targets in cardiovascular diseases.
Academic Article	Rho/Rho-associated coiled-coil forming kinase pathway as therapeutic targets for statins in atherosclerosis.
Academic Article	Rho GTPases, statins, and nitric oxide.
Academic Article	ROCKs as immunomodulators of stroke.
Academic Article	Physiological role of ROCKs in the cardiovascular system.
Academic Article	Inhibition of Rho-kinase attenuates endothelial-leukocyte interaction during ischemia-reperfusion injury.
Academic Article	A combination of increased Rho kinase activity and N-terminal pro-B-type natriuretic peptide predicts worse cardiovascular outcome in patients with acute coronary syndrome.
Academic Article	ROCK1 mediates leukocyte recruitment and neointima formation following vascular injury.
Academic Article	RhoA/ROCK signaling is essential for multiple aspects of VEGF-mediated angiogenesis.
Academic Article	FHL2 prevents cardiac hypertrophy in mice with cardiac-specific deletion of ROCK2.
Academic Article	Effect of aldosterone-producing adenoma on endothelial function and Rho-associated kinase activity in patients with primary aldosteronism.
Academic Article	Rho kinase (ROCK) inhibitors.
Academic Article	Rho-associated kinase activity is a predictor of cardiovascular outcomes.
Academic Article	Exogenous nitric oxide inhibits Rho-associated kinase activity in patients with angina pectoris: a randomized controlled trial.
Academic Article	Rho-associated kinase activity is an independent predictor of cardiovascular events in acute coronary syndrome.
Academic Article	ROCK insufficiency attenuates ozone-induced airway hyperresponsiveness in mice.
Academic Article	Gene variations of ROCKs and risk of ischaemic stroke: the Women's Genome Health Study.
Academic Article	Increased leukocyte ROCK activity in patients after acute ischemic stroke.
Academic Article	Peripheral plasma vitamin D and non-HDL cholesterol reflect the severity of cerebral cavernous malformation disease.
Academic Article	Interventional Transcatheter Closure Ameliorates the Leukocyte Rho Kinase Activities among Patients with Patent Ductus Arteriosus.
Academic Article	Rho Kinases and Cardiac Remodeling.
Academic Article	Two functional polymorphisms of ROCK2 enhance arterial stiffening through inhibiting its activity and expression.
Academic Article	RhoA Kinase Inhibition With Fasudil Versus Simvastatin in Murine Models of Cerebral Cavernous Malformations.
Academic Article	Role of ROCK2 in CD4+ cells in allergic airways responses in mice.
Academic Article	Decreased thromboembolic stroke but not atherosclerosis or vascular remodelling in mice with ROCK2-deficient platelets.
Academic Article	ROCK as a therapeutic target for ischemic stroke.
Academic Article	Neuroprotection Mediated by Upregulation of Endothelial Nitric Oxide Synthase in Rho-Associated, Coiled-Coil-Containing Kinase 2 Deficient Mice.
Academic Article	Eplerenone improves endothelial function and arterial stiffness and inhibits Rho-associated kinase activity in patients with idiopathic hyperaldosteronism: a pilot study.
Academic Article	The Rho Kinase Isoforms ROCK1 and ROCK2 Each Contribute to the Development of Experimental Pulmonary Fibrosis.
Academic Article	Rho Kinase Inhibition Blunts Lesion Development and Hemorrhage in Murine Models of Aggressive Pdcd10/Ccm3 Disease.
Academic Article	A Brain-Targeted Orally Available ROCK2 Inhibitor Benefits Mild and Aggressive Cavernous Angioma Disease.
Academic Article	Targeting Rho-associated coiled-coil forming protein kinase (ROCK) in cardiovascular fibrosis and stiffening.
Academic Article	Serine-threonine kinase ROCK2 regulates germinal center B cell positioning and cholesterol biosynthesis.
Academic Article	Vascular Stiffening Mediated by Rho-Associated Coiled-Coil Containing Kinase Isoforms.
Academic Article	Role of Rho-Associated Kinase in the Pathophysiology of Cerebral Cavernous Malformations.

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rho Associated Kinases